About
Proteomics Research Infrastructure (PRI) is a state-of-the-art mass spectrometry (MS) based proteomics facility located at the University of Copenhagen. PRI offers proteomic support at the highest technical level to academic and non-academic research groups from the Nordic countries. This includes consultation on proteomics methods, sample preparation on fully automated sample prep pipelines, measurement on the newest MS instrumentation, as well as data analysis by proteomic data experts.
PRI is funded by the Novo Nordisk Foundation (NNF) and scientifically linked to the Novo Nordisk Foundation Center for Protein Research (CPR) at the University of Copenhagen.
MS instrumentation
HPLCs
- Evosep ONE (4x)
- Thermo Vanquish Neo (4x)
- Thermo EASYnLC (2x)
Sample Automation
Below is a list of our users publications where data was acquired at PRI:
- Sonne, A., Peverelli, L., Hernandez-Lain, A., Dominguez, C., Andersen, J.L., Milone, M., Beggs, A.H., and Ochala, J. (2023). Myosin post-translational modifications and function in the presence of myopathy-linked truncating MYH2 mutations. Cell Physiology.
- Cugusi, S., Mitter, R., Kelly, G., Walker, J., Han, Z., Pisano, P., Wierer, M., Stewart, A., and Svejstrup, J.Q. (2022) Heat shock induces premature transcript termination and reconfigures the human transcriptome. Molecular Cell 82, 8, 1573-1588.
- Bastrup, J., Aalkjær, C., and Jepps, T.A. (2022). Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries. JBC 298, 1, 101512
- Colding, C., Autzen, J., Pfander, B., and Lisby, M. (2021). Cdc48 targets INQ-localized Mrc1 to facilitate recovery from replication stress. bioRxiv