Publications

Selected publications. For a full list, see below.

Discovery Proteomics (Deep Phenotyping & Systems Biology)

2025 – Cherkaoui et al – Reprogramming neuroblastoma by diet-enhanced polyamine depletion Nature

2025 – Stocks et al – Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise Science Advances

2025 – Moreno-Justicia et al – Human Skeletal Muscle Fiber Heterogeneity Beyond Myosin Heavy Chains Nature Communications

Signaling Proteomics

2025 – Kjærgaard Larsen et al – Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes Cell

2025 – Kjærgaard Larsen et al – Phosphoproteomic Analysis Identifies REPS1 as an Insulin- and Exercise-Responsive Signal Transducer Cell Reports Medicine

2024 – Achter et al – In-depth phosphoproteomic profiling of the insulin signaling response in heart tissue Cardiovascular Diabetology

Interaction Proteomics (AP-MS & Proximity Labeling)

2025 – Zheng et al – Pupylation-based proximity labeling reveals regulatory factors in cellulose biosynthesis in Arabidopsis Nature Communications

2024 – Blears et al – Redundant Pathways for Removal of Defective RNA Polymerase II Transcription Complexes Molecular Cell

2026 – Lund V.C. et al. - A Syd and RUFY dynein adaptor complex mediates axonal circulation of dense core vesicles - Journal of Cell Biology

All publications with PRI contribution

 

 

 

Kompocholi S. et al. - SCAF1 driven polyadenylation site usage regulates mRNA isoform expression and neuronal differentiation - bioRxiv

Mandleywala K. et al. - A dietary pan-amino acid dropout screen in vivo reveals a critical role for histidine in T-ALL - bioRxiv

Kassouf T. et al. - Translational Fidelity Maintained by ZNF598-Dependent Ribosome Resolution Enables Cellular Adaptation to High Energy Demand - bioRxiv

Markis K. et al. - Hepatic metabolic reprogramming in male mice during short-term caloric restriction involves enhanced glucocorticoid rhythms - Nature Communications

Schlabs F. et al. - Skeletal Muscle Proteome Remodeling Across Metabolic Phenotypes Reveals AMPKγ2-Dependent Exercise Training Adaptation - SSRN

Pinto A. et al. - Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease - Aging cell

Dall, M. et al. - Hepatocyte dedifferentiation in 2D culture reveals extensive transcriptomic and proteomic rewiring - Hepatology Communications

Houlberg Jensen A-S et al. - Diagnostics of Autoimmune Hepatitis Enabled by Non-Invasive Clinical Proteomics - Aliment Pharmacol Ther

Kuznetsova K. et al. - MODY mutations in transcription factors HNF1A and HNF1B affect the production of interferon signaling proteins: evidence at the proteome level - bioRxiv

Thomas Q.A. et al. - Oxidative stress triggers RNAPII arrest through PARylation and DNA damage - bioRxiv

Sørensen J. et al. - Proteomic and phospho-proteomic longitudinal signatures of human skeletal muscle in lung cancer cachexia - bioRxiv

Ali M.S. et al. - Breast cancer cell-conditioned media inhibit growth and reduce basal and insulin-2 stimulated glucose uptake by inhibiting Rac1 activation in rat myotubes - The Journal of Physiology

Melhedegaard E.G. et al. - Myosin inhibition partially rescues the myofiber proteome in X-linked myotubular myopathy - JCI insight

Aljabbari A. et al. - Hydrophobic drug particles adopt a complex biomolecular corona in ex vivogastrointestinal fluids - Journal of Controlled Release

Cherkaoui S. et al. - Reprogramming neuroblastoma by diet-enhanced polyamine depletion - Nature

Achter J.S. et al. - Quantitative proteomics of formalin-fixed, paraffin-embedded cardiac specimens uncovers protein signatures of specialized regions and patient groups - Nature Cardiovascular Research

Galera, M.R. et al. - Impact of cell culture transition on adipose-derived mesenchymal stromal cells: Multi-omics analysis of small- vs large-scale production - Methods & Clinical Development

Raun S. et al. - Skeletal muscle Rac1 mediates exercise training adaptations towards muscle glycogen resynthesis and protein synthesis - Redox Biology

Sauerland M.B. et al. - Scalable Acid-Aided Lysis of Skin Samples Improves Proteome Coverage - Journal of Investigative Dermatology

Olthof A. et al. - Systems-level feedback loops maintain gene expression homeostasis following RNA polymerase II dosage perturbation - bioRxiv

Kissow J. et al. - Global proteomics reveals distinct muscle adaptations to menstrual cycle phase-based sprint interval training in endurance-trained females - Molecular and Cellular Proteomics

Schmidt J.H. et al. - Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs - Science advances

Ansbøl J. et al. - Autophagic degradation of EIN3 ensures developmental plasticity and recovery from environmental stress in Arabidopsis - bioRxiv

Fan Y. et al. - Polypeptides synthesised by common bacteria in the human gut improve rodent metabolism - Nature Microbiology

Kjærgaard Larsen J. et al. - Phosphoproteomic Analysis Identifies REPS1 as an Insulin- and Exercise-Responsive Signal Transducer to Glucose Uptake in Skeletal Muscle - Cell reports medicine

Kurgan N. et al. - Body Fluid Proteomic Landscape of Acute Exercise - bioRxiv

Sanchis P. et al. - The metabolic and molecular mechanisms underlying running-induced energy compensation - bioRxiv

Seaborne R. et al. - Integrated single-cell functional-proteomic profiling of human skeletal muscle reveals a shift in cellular specificity in nemaline myopathy - The Journal of Physiology

Laitila J. et al. - Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper-contractility - The Journal of Physiology

Kjærgaard Larsen J. et al. - Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes - Cell

Lewis C.T.A. et al. - Dysregulated Skeletal Muscle Myosin Super-relaxation in Type II, but Not Type I, Diabetes Mellitus - Diabetologica

Arendrup F. et al. - A tripartite cell-free translation system to study mammalian translation - Nature Protocols

Chubanava S. et al. - NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging - Cell Metabolism

Ratanasopa K. et al. - Sorghum bicolor membrane steroid binding protein 1 can bind heme and remodel ER membranes - Plant & Cell Physiology

Fagernäs Z. et al. - New methods on the block: Taxonomic identification of archaeological bones in resin-embedded sediments through palaeoproteomics - bioRxiv

Stewart C.A. et al. - Defining the role of fibroblasts in skin expansion - bioRxiv

Zheng S. et al. - Pupylation-Based Proximity Labeling Unravels a Comprehensive Protein and Phosphoprotein Interactome of the Arabidopsis TOR Complex - Advanced Science

Moreno-Justicia R. et al. - Human Skeletal Muscle Fiber Heterogeneity Beyond Myosin Heavy Chains - Nature Communications

Kihara S. et al. - The “gut” corona at the surface of nanoparticles is dependent on exposure to bile salts and phospholipids - Journal of Colloid and Interface Science

Van der Pjil R. et al. - Increased cardiac myosin super-relaxation as an energy saving mechanism in hibernating grizzly bears - Molecular Metabolism

Samadova D. et al. - Salivary proteomics and metaproteomics identifies distinct molecular and taxonomic signatures of type-2 diabetes - Microbiome

Zheng S. et al. - Pupylation-based proximity labeling reveals regulatory factors in cellulose biosynthesis in Arabidopsis - Nature Communications

Stocks B. et al. - Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise - Science advances

 

 

Vašíček J. et al. - ProHap enables human proteomic database generation accounting for population diversity - Nature Methods

Blears D. et al. - Redundant Pathways for Removal of Defective RNA Polymerase II Transcription Complexes at a Promoter-Proximal Pause Checkpoint. - Molecular Cell

Phadke K. et al. - Atrial cardiomyopathy resulting from loss of plakophilin-2 expression: Response to adrenergic stimulation and implications for the exercise response - The Journal of Physiology

Aravena-Calvo J. et al. - Global organization of phenylpropanoid and anthocyanin pathways revealed by proximity labeling of trans-cinnamic acid 4-hydroxylase in Petunia inflata petal protoplasts - Frontiers Plant Sciences

Moesgaard L. et al. - Muscle fiber proteomics reveals sex- and fiber type-specific adaptations to resistance training - bioRxiv

Laitila J. et al. - Myosin ATPase inhibition fails to rescue the metabolically dysregulated proteome of nebulin-deficient muscle - The Journal of Physiology

Vidal-Calvo E.E. et al. - Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate - Nature Communications

Yeung H. Y. et al. - Fish-hunting cone snail disrupts prey’s glucose homeostasis with weaponized mimetics of somatostatin and insulin - Nature Communications

Achter J.S. et al. - In-depth phosphoproteomic profiling of the insulin signaling response in heart tissue and cardiomyocytes unveils canonical and specialized regulation - Cardiovascular Diabetology

Lubberding A. et al. - GLP-1 increases heart rate by a direct action on the sinus node - Cardiovascular Research

Lewinska M. et al. - Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma - Gastroenterology

Lewis C.T.A. et al. - Remodelling of skeletal muscle myosin metabolic states in hibernating mammals. - eLife

Petersen J. et al. - GLP-1-directed NMDA receptor antagonism for obesity treatment - Nature

Bradic I. et al. - Lanifibranor reduces inflammation and improves dyslipidemia in lysosomal acid lipase-deficient mice - Gastro Hep Advances

Lathe R.S. et al. - NKS1/ELMO4 is an integral protein of a pectin synthesis protein complex and maintains Golgi morphology and cell adhesion in Arabidopsis - PNAS

Ebstrup E. et al. - NBR1-mediated selective autophagy of ARF7 modulates root branching - EMBO reports

Luige J. et al. - Predicting nuclear G-quadruplex RNA-binding proteins with roles in transcription and phase separation - Nature Communications

Samadova D. et al. - Plasma proteome profiling reveals metabolic and immunologic differences between Anorexia Nervosa subtypes. - Metabolism

Fadahunsi N. et al. - Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment. - Science advances

 

 

Kjærgaard Larsen J. et al. - High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue. - Science advances

Lopez A.R. et al. - Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence. - Cell reports

Sonne A. et al. - Abnormal myosin post-translational modifications and ATP turnover time associated with human congenital myopathy-related RYR1 mutations. - Acta physiologica (Oxford, England)

Bastrup J. et al. - Proteomic mapping reveals dysregulated angiogenesis in the cerebral arteries of rats with early-onset hypertension. - The Journal of biological chemistry

Saenz C. et al. - Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner - Microbiology spectrum

Häfner S.J. et al. - Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions - Developmental Cell

Sonne A. et al. - Myosin post-translational modifications and function in the presence of myopathy-linked truncating MYH2 mutations - American Journal of Physiology-Cell Physiology

Cugusi S. et al. - Heat shock induces premature transcript termination and reconfigures the human transcriptome. - Molecular cell

Bastrup J. et al. - Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries - The Journal of biological chemistry

Colding C. et al. - Cdc48 targets INQ-localized Mrc1 to facilitate recovery from replication stress - bioRxiv